Q. How long do I need to take Fastin™?
A. Fastin™ should be taken until your desired weight loss goals are met. The
ultimate duration is entirely dependent upon the amount of weight you need
to lose.
Q. Who should or should not use Fastin™?
A. Fastin™ is intended to help women and men who have difficulty losing
weight. Unlike prescription medications, Fastin™ will work regardless of the
amount of weight you need to lose. Fastin™ has a strong record of safety and
is virtually safe for all people. If you are pregnant or lactating you
should not take Fastin™.
Q. What are the major effects of Fastin™?
A.
(1) Increases the Metabolic Rate, Promoting Thermogenesis (The Burning of
Stored Body Fat).
(2) Increases the Release of Norepinephrine and Dopamine for Dramatic Weight
Loss.
(3) Promotes Extreme Energy and Does Not Cause the "Jitters."
Q. What is Fastin?
A. Fastin was based on a drug called Phentermine is a stimulant that is
similar to an amphetamine. Phentermine is an appetite suppressant that
affects the central nervous system. Phentermine is used togther with diet
and exercise to treat obesity (overweight) in people with risk factors such
as high blood pressure, high cholesterol, or diabetes.The new active
ingredient in Fastin is (ß-methyl-phenethylamine) 37.5mg which may overlap
and should not be combined with other phenethylamines including phentermine,
fenfluramine, amphetamine, cathinone and the synthetic drug
dextroamphetamine and methylphenidate or other substituted phenethylamines.
Why is Fastin good for Weight Loss
Fastin is considered to be a Sympathomimetic appetite suppressant.
Sympathomimetic appetite suppressants are used in the short-term treatment
of obesity. Their appetite-reducing effect tends to decrease after a few
weeks. The sympathomimetic appetite suppressants (FASTIN ) can help you to
lose weight while you are learning new ways to eat and to exercise. Changes
in eating habits and activity level must be developed to truly benefit from
Fastin
Fastin Warnings
Do not take Fastin a if you are allergic to other stimulants, or if you
have:
# Heart disease or high blood pressure
# Arteriosclerosis (hardening of the arteries)
# An overactive thyroid
# Glaucoma
# If you are in an agitated state
# If you have a history of drug or alcohol abuse.
PRODUCT WARNING:
Read all directions carefully. Use Fastin a only as directed. Exceeding the
recommended dosage will not increase your results. Fastin a contains active
(Beta-methyl-phenethylamine) 37.5mg which may overlap and should not be
combined with other phenethylamines including phentermine, fenfluramine,
amphetamine, cathinone and the synthetic drug dextroamphetamine and
methylphenidate or other substituted phenethylamines. Do not take Fastin a
in the evening because it may cause sleep problems (insomnia). As with all
weight loss plans, consult your physician prior starting a diet or exercise
plan or including any dietary supplement. Do not take Fastin a if you are
pregnant or lactating.
(phentermine) side effects
When taking Phentermine, one should be advised that they should seek
emergency medical help if you have any of these signs of an allergic
reaction: hives; difficulty breathing; swelling of your face, lips, tongue,
or throat. Other serious side effects that will require medical attention
are: chest pain, swelling in your ankles or feet, feeling light-headed,
fainting, or feeling short of breath, even with mild exertion; If you
experience any of these side effects, stop using Phentermine immediately
fast or uneven heartbeat;unusual thoughts or behavior, feeling restless or
confused; orincreased blood pressure (severe headache, blurred vision,
trouble concentrating, chest pain, numbness, seizure).feeling nervous or
anxious;headache, dizziness, tremors;trouble sleeping (insomnia);dry mouth
or an unpleasant taste in your mouth;diarrhea or constipation; or itching.
Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially
bothersome. Lose Weight
Fastin™ !
By: Mark Wright, M.D.
Over the past nine years, I have worked with the top researchers,
pharmacologists, and physicians from Hi-Tech Pharmaceuticals to develop the
perfect diet pill. Hi-Tech has put out several blockbuster weight loss aids
such as Lipodrene®, Stimerex-ES®, and Lipodrene Xtreme®, to name a few. One
thing most people do not know about Hi-Tech is its direct response business.
Over the past ten years, Hi-Tech has had three weight loss sister companies
that formulate, market, and sale diet aids direct to the public. “So what?”
you may ask. Well, Hi-Tech offers a 100% money-back guarantee to anyone not
satisfied. Hi-Tech marketed over 20 diet aids with different ratios of
ingredients until it hit pay dirt. Hi-Tech sold direct to over 500,000
consumers and was able to track refund rates and compare them versus
re-order rates. Lipodrene® and Stimerex-ES® were launched by Hi-Tech to
retailers as they were the two best products Hi-Tech developed out of the 20
test marketed. No other company has the data, feedback, or technology to
create such products. With the evolution of Hi-Tech’s pharmacological
research into weight loss compounds, I believe we have created our finest
masterpiece!
As a bariatric (weight loss) physician, I prescribed Fastin™ for decades as
a prescription drug to my patients with overwhelming success. When
SmithKline Beecham (now known as GlaxoSmithKline) withdrew Fastin™ from the
market, it sent shockwaves through the weight loss industry. Since its exit
from the market, Hi-Tech has been doing some exhaustive research and
development on a new formula with pharmaceutical fat mobilization and
apoptosis agents to create the new and improved Fastin™. Fastin’s
effectiveness produced an almost cult following, Fastin™ was unmatched in
its efficacy until it was taken off the market by GlaxoSmithKline. Unwilling
to attach the name “Fastin” to just any ole fat burning fat burning formula,
Hi-Tech has spent a countless amount of time and resources to find a formula
equal to or superior to the original Fastin, in terms of feeling and effect.
Finally, after several years of research on this project, Hi-Tech developed
a formula that is every bit as good (if not better) than the original Fastin
formula. Hi-Tech is so confident in Fastin that they are staking their name
on it in many ways as the leaders in the weight loss industry…as the shoes
Hi-Tech had to fill were very large.
Although the feeling and effect of Hi-Tech’s Fastin™ is at least as good as
the original, the formula has changed in significant ways. The old Fastin
formula was formulated around Phentermine HCL, while the new Fastin is
formulated around phenylethylamine HCL and derivatives of this molecule.
Phenylethylamine is an amazing compound that is naturally present in human
fluids and tissue. This compound is probably the cleanest stimulant ever
researched, which has the remarkable ability to stimulate the central
nervous system, without causing nervousness or the jittery feeling.
Phenylethylamine is found in chocolate and is responsible for its effects on
mood, appetite, and sense of well-being.
Incenerate Fat – Say Goodbye to your Lovehandles!
Fat mobilization is a new breakthrough in the field of weight loss. As a
bariatric physician (weight-loss physician), I try to stay at the forefront
of the diet industry. The newest thermogenic breakthrough introduced into
the market is called Lipid Mobilization, which helps you burn body fat
without exercise. In vitro research shows that lipid mobilization is one of
the processes that releases fat into the bloodstream to be burned as energy.
On the fat cell’s surface are receptors that signal the cell to hold stored
fat. Natural Alpha-2 antagonists have been shown to switch off these
receptors. Freed fatty acids can then move out of the cell and into the
bloodstream. These released fats are shuttled away from fat and prevented
from simply being re-deposited. This is especially effective in the stubborn
abdominal and hip areas of both men and women. Best of all, when taken
before exercise, fat mobilizers are shown to boost lipolysis (the process of
mobilizing fats from cells) and increase blood serum free fatty acid levels
both during and after exercise.
The extent of which exercise burns body fat is totally dependent upon the
rate of lipolysis. Lipolysis is the rate at which fat is mobilized from fat
cells and enters the bloodstream as free fatty acids (FFAs). Exercise
triggers lipolysis, and highly trained individuals possess a greater
lipolytic rate, an ability to “burn” more fat during exercise, than
untrained people. If you want the greatest possible fat-burning effect from
exercise, then increasing your rate of lipolysis is the way to do it. A high
rate of lipolysis ensures greater fat mobilization by the liver and
mitochondria in muscle cells during exercise. In turn, this process ensures
that a greater concentration of body fat is burnt during exercise. The
impact of fat mobilizers on post-exercise fat metabolism is particularly
evident 30 minutes after cardio exercise. One study showed that FFA levels
in the bloodstream doubled in those that took a fat mobilizer prior to
exercise compared to a placebo.
Many physiological factors stimulate and inhibit the breakdown of adipose
tissue into free fatty acids and glycerol and their mobilization into the
bloodstream to be used as fuel by other cells and tissues. Fasting, feeding,
exercise, and stress have pronounced and rapid effects on lipolysis via
hormones and other endogenous substances. As well, clinical conditions such
as diabetes and obesity are associated with alterations in lipolysis. Age
and gender are also of importance.
Insulin and catecholamines are the main regulatory hormones of lipid
mobilization. Insulin is the major antilipolytic hormone because of its
effects on enzymes within the adipocyte. Insulin also enables the entry of
glucose into the cells by inducing glucose transporter activity. Glucose
serves as the backbone for the glycerol molecule to which fatty acids attach
and form triacylglycerols. The catecholamines serve a dual function. You
must first become acquainted with fat cell biology to comprehend the
regulation of fat loss. Lipogenesis and lipolysis can be considered the Yin
and Yang of adipose tissue metabolism. Lipogenesis is the process of fat
accumulation and lipolysis is that of fat breakdown and release into the
bloodstream.
Fat Mobilizers and Their Unique Fat Burning Abilities
There are physiological differences in fat cells, depending upon where they
are located in the body. Fat cells located in the gut (visceral adipocytes)
differ from fat cells located in the lower regions of the body (hips,
thighs, lovehandles). Fat cells within the stomach contain a lot of
beta-receptors. These cells respond to release fat when stimulated by the
classic “fat-burners,” such as caffeine, ephedrine, and synephrine. These
compounds stimulate lipolysis specifically by increasing norepinephrine
delivery to the visceral fat cells and catecholamine secretion that
activates the beta-receptors and increases CAMP within cells. However, fat
cells located around the hips, and lovehandles characteristically contain
very few beta-receptors and respond poorly to catecholamine release that is
induced by exercise and beta-stimulants. However, these lower body fat cells
contain a lot of alpha adrenoreceptors. Alpha-receptors are tricky and
obstinate if you want them to release their fat stores. When stimulated,
these receptors activate other proteins that inhibit adenylcyclase, thus
antagonizing the ability of beta-adrenoreceptors to boost CAMP generation,
and therefore, shut down the usual fat mobilization process. Basically, when
taking caffeine, ephedrine, and synephrine supplements in an effort to
stimulate fat loss, the alpha-receptors on lower-body fat cells say “No! No
fat mobilization for you!” Fat cells within the lower half of the body
contain a higher concentration of alpha-receptors and lower concentration of
beta-receptors. Therefore, they are quite resistant to lipolysis. Women
characteristically carry more fat on their hips and thighs than men do, and
this difference in fat cell structure is one reason why most women have a
tougher battle with fat loss…Until Now!
Apoptosis – A Novel Approach to Weight Loss
Hi-Tech has recognized for years that the active components in Hi-Tech’s fat
loss products exerted their influence on fat loss through mechanisms of
action attributable to increased lipolysis, decreased Lipogenesis, and more
metabolically desirable fat mobilization. However, over the past five years
of Research and Development, Hi-Tech began testing a theory that some of the
beneficial effects of Lipodrene® and Stimerex-ES® were also actually due to
their effect on elimination of entire fat cells, or apoptosis. Apoptosis is
a form of cell suicide that plays a vital role in the maintenance of
cellular homeostasis, but for weigh loss it causes cell death (specifically,
fat cell death). It was once believed that the total number of adipocytes
(fat cells) remained fairly constant over one’s lifetime; however studies
over the last ten years have shown that adipocytes can be both lost and
gained, and it is becoming increasingly recognized that fat cells have a
finite life cycle and can be eliminated by apoptosis.
Apoptosis is a novel approach to help people lose fat. Since research began
several years ago on this activity of the compounds in Lipodrene®, Hi-Tech
has been investigating many plant extracts and other natural substances for
their ability to reduce adipose tissue mass by reducing the number of
adipocytes through the mechanism of apoptosis. We have identified a number
of agents that may induce apoptosis of adipose tissue, and found that some
catecholamines and beta-adrenergic receptor agonists are prone to induce
adipose tissue apoptosis when administered orally. These compounds include:
clenbuterol, ractopamine, phenylethylamine, and alkaloids from acacia
rigidula extract, including b-phenylethylamine, N-Methyl-b-phenylethylamine,
and R-beta-methylphenylethylamine. These compounds appear to have the
ability to increase the rate of apoptosis in adipose tissue cells,
specifically white adipose tissue cells. It is suggested that Fastin’s
active components demonstrate a wide array of action on adipocytes,
including increased lipolysis, decreased Lipogenesis, decreased cell
proliferation, and increased adipogenesis (blocking immature fat cells from
maturing and storing lipids). In addition, Fastin assists in more effective
lipid mobilization.
Fastin brings forth a trifecta of advancements in the fat loss arena: 1) a
sophisticated manufacturing process that utilizes a dual delivery system
technology for specific control of rapid and sustained release of its active
compounds, 2) a proprietary active compound formulation that trumps the
existing field of fat loss compounds and puts even ephedra in the back seat,
3) a novel approach to fat loss through triggering fat cell death
(apoptosis).
Hi-Tech Pharmaceuticals recently launched Fastin™ into the weight loss
arena. In recent months, Hi-Tech acquired rights to Fastin from King
Pharmaceuticals. King Pharmaceuticals manufactured the brand name product
Fastin (phentermine HCL) for Smith Kline Beecham. In December 1998,
SK-Beecham withdrew Fastin from the market. Hi-Tech Pharmaceuticals has
reformulated Fastin and expects it to be their top weight loss aid. Fastin
is a pharmaceutical-grade dietary supplement indicated for weight loss in
extremely overweight individuals. Fastin has booth immediate and delayed
release profiles for appetite suppression, energy, and weight loss. Fastin
is comprised of nine pharmaceutical-grade fat loss catalysts at precise
ratios in order to achieve its extraordinary results. Fastin’s proprietary
formula includes the following:
R-Beta-methylphenylethylamine HCL – this amazing compound is the active
isomer of MPEA much like 1R, 25 Norephedrine was of PPA years ago. This
compound stimulates norepinephrine unlike any other and leads to appetite
suppression, energy, and ultimate fat loss.
Methylphenylethylamine tartrate – this is the racemic version of MPEA bound
to tartaric acid, which keeps the molecule stable. This compound is found in
Hi-Tech’s line and is a rising star of the fat loss industry.
N-methyl-phenylethylamine – is another isolated amine from acacia rigidula
that is both for stimulating fat burning and energizing effects. This is the
N-methyl derivative of the compound B-Phenylethylamine. This is a very
potent compound for all who lack a chemistry degree.
Methylsynephrine – is phenolic B-Phenylethylamine found in Acacia Rigidula
and some cacti, which produces considerable nervous system stimulation
(CNS). With Hi-Tech’s research over the past five years on Acacia Rigidula
(as Thermo-Rx®), we have identified and isolated several key
phenylethylamine alkaloids. The newest of which is methylsynephrine. The
alkaloids from the acacia rigidula are biologically and physiologically
similar to those found in ephedra, and possess properties that are shared
with ephedra alkaloids. Scientifically, this is in part due to the
similarities in pharmacokinetics and pharmacodynamics. The most obvious
similarity is that acacia alkaloids, like the ephedra alkaloids, readily
pass into the brain. The main factor governing the transfer of small
molecules into the central nervous system is lipophilicity. The distribution
of drugs and/or compounds into the CNS from the blood is unique, because
functional barriers are present that restrict entry of drugs into this
critical site. One reason for this is that the brain capillary endothelial
cells have continuous tight junctions; therefore, drug penetration into the
brain depends on transcellular rather than paracellular transport between
cells. The unique characteristics of percipaillary gilial cells also
contribute to the blood-brain barrier. At the choroids plexus, a similar
blood-cerebrospinal fluid (CSF) barrier is present, except that it is
epithelila cells that are joined by tight junctions rather than endothelial
cells. As a result, the lipid solubility of the nonionized and unbound
species of the drug is an important determinant of its uptake by the brain;
the more lipophilic it is, the more likely it is to cross the blood-brain
barrier. This situation is used in drugs design to alter the brain
distribution, which is the case with drugs like amphetamine, phentermine,
and benzphetamine. As you can see from the comparison of the structures of
ephedrine, norephedrine, and methylsynephrine they all possess the b-methyl
substituent of the aliphatic sidechain, which is characteristic of ephedrine
and its congeners, as well as methylsynephrine, thus further increasing
lipophilicity.
What is a suitable substitute for ephedra? How about another beta agonist?
Methylsynephrine is just the answer that the industry has been waiting on
for years! The sympathetic nervous system is involved in the regulation of
energy. Therefore, pharmacological manipulation of the system offers a
mechanism of targeting a reduction in excess body fat stores. Many
beta-adrenergic agonists are known to increase muscle mass while
concurrently decreasing fat mass. Prolonged treatment with sympathomimetic
compounds reduces energy intake and increases energy expenditure. The beta
2&3 receptors appear to be responsible for the lipolytic and thermogenic
effects of adrenergic agents, while interaction with beta-1 and to a much
lesser extent, beta-2 control cardiac effects. Accordingly, the ideal fat
loss compound would be one identical to acacia rigidula and especially
methylsynephrine. Until now, there has never been a beta-adrenergic compound
like methylsynephrine that can stimulate lipolysis and increase resting
metabolic rate like ephedra.
Theobromine – is the primary methylxanthine found in products of the cocoa
tree, Theobroma cocao. As a member of the methylxanthine family, it is
thought to elevate levels of serotonin, the same action as the popular
anti-depressants. Theobromine has a lot of research that shows its
extraordinary effects on fat loss, appetite suppression, and mobilization of
fatty deposits. Theobromine acts as a mild diuretic and stimulant, which
creates a synergistic effect with caffeine.
Phenylethylamine HCL – this amazing compound is probably the cleanest
stimulant ever researched, and it is naturally present in human fluids and
tissues. Although categorized as a stimulant, it has the remarkable ability
to simulate the central nervous system without causing nervousness or the
jittery feeling. Phenylethylamine is found in chocolate and is responsible
for its effects on mood, appetite, and sense of well-being. Until recent
discoveries, PEA, or phenylethylamine, was rapidly destroyed within the
body. If included with novel delivery systems, phenylethylamine HCL is
provided “safe transport” and this metabolic fate is avoided and
pharmacological activity becomes extremely apparent. This catecholamine
precursor is responsible for elevating the metabolic rate and promoting a
sense of satiety. Phenylethylamine acts on alpha-receptors in the brain, as
do norepinephrine and certain prescription anti-obesity drugs. It is also
believed to cause the release of dopamine in the pleasure sensing areas of
the brain. Phenylethylamine HCL has a close chemical relationship to
pharmaceutical stimulants, because it is the “backbone” of many
pharmaceutical compounds.
Yohimbine HCL – has been shown in many clinical trials to effectively block
alpha 2 adrenoreceptors. These studies have found that yohimbine increases
the amount of non-esterfied fatty acids (NEFA’s) a product of lipolysis (the
breakdown of fat), in the blood-stream for both lean and overweight
subjects. There are a number of feedback mechanisms that prevent the release
of norepinephrine (NE), one of the body’s primary lipolytic hormones. When
NE is released, such as when taking methylsynephrine and acacia rigidula, it
stimulates both the alpha and beta adrenoreceptors. Stimulation of the beta
adrenoreceptors has the opposite effect, preventing the release of NE and
lipolysis. Yohimbine prevents this negative feedback mechanism, and works in
a synergistic fashion with the other components to increase NE and lipolysis.
There are a number of reasons why alpha-2 inhibition is specifically useful.
First, while the beta-adrenergic system primarily controls lipolysis during
periods of intense activity, during rest, which makes up most of our day,
the alpha-adrenergic system is in control. Also, “stubborn fat” areas –
usually the abdominal area in men and the glutofemoral area in women –
contain a higher ratio of alpha-2 receptors, making yohimbine particularly
effective in these areas (whereas other drugs that increase NE may be
somewhat counterproductive). Finally, alpha-2 blockade increases blood flow
in adipose tissue, which prevents fat from being retained in the area.
Synephrine HCL – is a drug used primarily in fat loss, although the
effectiveness is minimal in Fastin. It is very popular and has been used as
an alternative to ephedrine (a substance with a history of controversy).
Synephrine is derived primarily form the fruit of a small citrus tree.
Caffeine Anhydrous USP – acts as a stimulant and thermogenic in humans, and
is commonly taken to boost energy or mental concentration. It will stimulate
the central nervous system and the metabolism. Once metabolized, caffeine
can increase lipolysis in the body. Caffeine may also increase the
effectiveness of other substances such as ephedrine or yohimbe, and was
incredibly popular in the commonly used ECA stack (ephedrine, caffeine, and
aspirin).
“What is in a Name?”
In Romeo and Juliet by Shakespeare, the character, Juliet says, “What is in
a name? That which we call a rose by any other name would smell as sweet.”
Hi-Tech has attached the name, Fastin, to the most effective diet aid of the
21st century. Hi-Tech expects to revive the cult following that Fastin
previously enjoyed. Hi-Tech also enjoys the challenge of living up to a
legend. In baseball, Ken Griffey, Jr. came into the league with big shoes to
fill in his hall of fame father’s Cincinnati Red eyes. Today, 593 home runs
later, “the natural,” as many call him, feels he achieved quite a bit more
than his father ever did in baseball, and did more than just fill his
father’s shoes. In NASCAR racing, Dale Earnhardt, Jr. has fans worldwide
expecting him to continue winning and live up to his father’s reputation –
which is that he was the best driver to ever get behind the wheel of a car.
Fastin by Hi-Tech Pharmaceuticals not only welcomes the challenge of living
up to a legend, but chose the name in order to have a tell set of shoes to
fill. Fastin is a world class fat burner that will help anyone needing to
lose weight. Whether you need to lose a little or a lot of weight – Fastin
is just what the doctor ordered!
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